TOR Serine-Threonine Kinases

A serine threonine kinase that controls a wide range of growth-related cellular processes. The protein is referred to as the target of RAPAMYCIN due to the discovery that SIROLIMUS (commonly known as rapamycin) forms an inhibitory complex with TACROLIMUS BINDING PROTEIN 1A that blocks the action of its enzymatic activity.

Also Known As:

FK506 Binding Protein 12-Rapamycin Associated Protein 1; FKBP12-Rapamycin Associated Protein; FKBP12-Rapamycin Complex-Associated Protein; Mammalian Target of Rapamycin; Mechanistic Target of Rapamycin Protein; RAFT-1 Protein; Rapamycin Target Protein; Target of Rapamycin Proteins; mTOR Protein; FK506 Binding Protein 12 Rapamycin Associated Protein 1; FKBP12 Rapamycin Associated Protein; FKBP12 Rapamycin Complex Associated Protein; Kinase, TOR; Kinase, TOR Serine-Threonine; Kinase, mTOR Serine-Threonine; Kinases, TOR Serine-Threonine; Kinases, mTOR Serine-Threonine; Protein Target, Rapamycin; Protein, RAFT-1; Protein, mTOR; RAFT 1 Protein; Rapamycin Protein Target; Serine-Threonine Kinase, TOR; Serine-Threonine Kinase, mTOR; Serine-Threonine Kinases, TOR; Serine-Threonine Kinases, mTOR; TOR Serine Threonine Kinase; TOR Serine Threonine Kinases; mTOR Serine Threonine Kinase; mTOR Serine Threonine Kinases; TOR Kinase; TOR Kinases; TOR Serine-Threonine Kinase; Target of Rapamycin Protein; mTOR Serine-Threonine Kinase; mTOR Serine-Threonine Kinases

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Transferases: 6589
    - Phosphotransferases: 42769
      - Phosphotransferases (Alcohol Group Acceptor)
        Protein Kinases: 9677
        Protein Serine-Threonine Kinases: 3588
        TOR Serine-Threonine Kinases: 5978
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Serine-Threonine Kinases: 3588
      - TOR Serine-Threonine Kinases: 5978

Peter Searle Selected Research

Peter Searle Research Topics

Disease

Drug/Important Bio-Agent (IBA)

Therapy/Procedure